Table 1 MARCO SNPs rs2278589 and rs6751745 are associated with pulmonary TB

From: MARCO variants are associated with phagocytosis, pulmonary tuberculosis susceptibility and Beijing lineage

SNP

rs2278589

rs6751745

Control genotype (11, 12, 22) (N, %)

194 (0.45)

190 (0.44)

48 (0.11)

210 (0.48)

181 (0.42)

43 (0.10)

PTB genotype (11, 12, 22) (N, %)

165 (0.37)

245 (0.55)

35 (0.08)

194 (0.43)

225 (0.50)

27 (0.06)

Genotypic (P, P*)

0.004

0.008

 

0.011

0.022

 

Dominant (P, P*, OR (95% CI))

0.101

0.202

1.5 (0.9-2.3)

0.035

0.070

1.7 (1.0–2.8)

Recessive (P, P*, OR (95% CI))

0.018

0.036

0.7 (0.5–0.9)

0.146

0.292

0.8 (0.6–1.1)

Heterozygous (P, P*, OR (95% CI))

0.001

0.002

1.6 (1.2–2.0)

0.009

0.018

1.4 (1.1–1.8)

  1. Abbreviations: OR (95% CI), odds ratio (95% confidence interval); SNP, single-nucleotide polymorphism.
  2. 1: majority allele; 2: minority allele; Dominant is the comparison of 22 vs (11+12).
  3. P=P-value.
  4. P*=corrected P-value, Bonferroni correction by two SNPs (P-values × 2). Bold entries indicate P-values <0.05.
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