Table 2 Summary of genotyped SNPs in MARCO

From: MARCO variants are associated with phagocytosis, pulmonary tuberculosis susceptibility and Beijing lineage

rs ID Location

Cases

Controls

Genotypic

 

PTB/TBM

11/12/22

11/12/22

HWE-P

P-values

rs7573346

PTB

131/233/84

122/213/105

0.524

0.175

4.9 Kb upstream

TBM

127/216/101

  

0.913

rs6748401

PTB

108/245/90

120/215/100

0.845

0.039

1.5 Kb upstream

TBM

115/223/109

  

0.788

rs1318645

PTB

109/246/92

119/215/100

0.879

0.057

3 bp upstream

TBM

115/223/109

  

0.815

rs4491733

PTB

104/240/102

114/228/93

0.290

0.593

intron 1

TBM

120/222/101

  

0.782

rs12998782

PTB

228/184/34

243/160/31

0.510

0.345

intron 1

TBM

239/168/33

  

0.883

rs17009726

PTB

331/110/8

340/94/6

0.863

0.456

intron 1

TBM

342/99/5

  

0.911

rs2278589

PTB

165/245/35

194/190/48

0.885

0.004

intron 3

TBM

194/203/47

  

0.871

rs1371562

PTB

289/141/15

284/138/15

0.724

0.998

intron 6

TBM

286/140/15

  

0.998

rs6761637

PTB

323/114/8

335/89/9

0.289

0.202

exon 10

TBM

333/101/6

  

0.519

rs6751745

PTB

194/225/27

210/181/43

0.663

0.011

intron 13

TBM

223/178/39

  

0.752

rs17796260

PTB

293/139/13

283/135/18

0.708

0.622

intron 13

TBM

292/136/14

  

0.739

rs3765035

PTB

145/251/49

152/220/60

0.164

0.210

intron 15

TBM

183/199/60

  

0.149

  1. Abbreviations: HWE, Hardy–Weinberg equilibrium; P, P-value; PTB, pulmonary tuberculosis; TBM, tuberculous meningitis.
  2. 1: majority allele; 2: minority allele. Bold values indicate the SNPs that have genotypic P-values <0.05.