Table 3 MARCO SNPs rs2278589 and rs6751745 are associated with level of CXR abnormality in PTB patients
Abnormality level | Genotype | Genotypic | Heterozygous | |||
|---|---|---|---|---|---|---|
GG | AG | AA | P-values | P-values | OR (95% CI) | |
rs2278589 | ||||||
Controls | 194 (0.45) | 190 (0.44) | 48 (0.11) | |||
Mild | 26 (0.38) | 39 (0.57) | 4 (0.06) | 0.112 | 0.052 | 1.7 (1.0–2.7) |
Intermediate | 67 (0.37) | 101 (0.56) | 13 (0.07) | 0.022 | 0.008 | 1.6 (1.1–2.3) |
Severe | 60 (0.35) | 96 (0.56) | 15 (0.09) | 0.026 | 0.007 | 1.6 (1.1–2.3) |
rs6751745 | ||||||
Controls | 210 (0.48) | 181 (0.42) | 43 (0.10) | |||
Mild | 31 (0.44) | 35 (0.50) | 4 (0.06) | 0.314 | 0.193 | 1.4 (0.8–2.3) |
Intermediate | 82 (0.45) | 90 (0.50) | 9 (0.05) | 0.055 | 0.068 | 1.4 (1.0–2.0) |
Severe | 68 (0.40) | 92 (0.54) | 11 (0.06) | 0.026 | 0.007 | 1.6 (1.1–2.3) |
