Fig. 1

LCR organization. The spatial arrangement of duplicated modules within LCRs A, B, C, and D is shown. The duplicated modules are shown as colored boxes, and the markers within them are shown above in the same color as the boxes. The orientation of each LCR is centromere to telomere. The sizes of the boxes are proportional to the estimated size of the respective module. Arrows below the duplicated modules indicate their orientation with respect to other copies within the same LCR as well as in other LCRs. The BAC/PAC/cosmid contig spanning each one of the LCRs is shown below each block. Unique markers flanking the LCRs are shown in black. Vertical dashed lines in B mark the boundaries of the gap in LCR-B.