Fig. 3
From: Cessation of enzyme replacement therapy in Gaucher disease

Response to ERT, cessation of therapy, and reinstitution in Patient 3. Histogram shows percent change in platelets (PLT), hemoglobin (HGB), ACE, and liver volume after 2 years of ERT, after 2 years off treatment, and after 1 year of reinstituted therapy. ERT dosages were 60 U/kg/2 weeks the first treatment year, 15 U/kg/2 weeks the second year, and 30 U/kg/2 weeks when therapy was restarted. The patient had a splenectomy at age 22 years and ERT began at age 49 years.