Fig. 3 | Genetics in Medicine

Fig. 3

From: Cessation of enzyme replacement therapy in Gaucher disease

Fig. 3

Response to ERT, cessation of therapy, and reinstitution in Patient 3. Histogram shows percent change in platelets (PLT), hemoglobin (HGB), ACE, and liver volume after 2 years of ERT, after 2 years off treatment, and after 1 year of reinstituted therapy. ERT dosages were 60 U/kg/2 weeks the first treatment year, 15 U/kg/2 weeks the second year, and 30 U/kg/2 weeks when therapy was restarted. The patient had a splenectomy at age 22 years and ERT began at age 49 years.

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