Fig. 3
From: Comparative evaluation of α-galactosidase A infusions for treatment of Fabry disease

Schematic of Fabry disease clinical manifestations for hemizygotes. The renal, cardiac, and central nervous system (CNS) disease are typically promoted by ischemia with transient ischemic attack (TIA), stroke, coronary insufficiency, and progressive renal deterioration. The precise mechanisms of disease initiation or progression are unknown.