Figure 1
From: Sporadic breast cancer among relatives of BRCA mutation carriers
Pedigree of a family with two sisters and a daughter/niece who developed breast cancer before the age of 50 years (family no. 1 in Table 1). One sister, who developed bilateral breast cancer at 41 years of age and then at 57 years of age, was a carrier of a BRCA1 mutation. The other sister and her daughter, who also developed breast cancer at a young age, had none of the known BRCA mutations or any mutation on sequencing of both BRCA genes. Numbers indicate age at time of breast cancer diagnosis.
