Fig. 2
From: CFTR 5T variant has a low penetrance in females that is partially attributable to its haplotype
The 5T variant has three different haplotypes in our test samples. Direct sequence analysis for exons 9 and 10 was performed on genomic DNA samples compound heterozygous for the ΔF508 mutation and the 5T variant. Portions of intron 8 and exon 10 representing each haplotype of the 5T variant: (a) 11TG-5T-470M; (b) 12TG-5T-470V; (c) 13TG-5T-470M. Sequencing reactions from forward (upper) and reverse (lower) directions.
