Fig 3

Phenotypes of biallelic GJB2 genotypes. Individuals were classified according to their reported mutation type (two T variants, one T, and one NT variant, or two NT variants) and their reported phenotypes. Unclassifiable refers individuals for whom phenotypic information was available but was difficult to categorize. If hearing loss was reported as consecutive ranges (such as mild to moderate), the more severe phenotype was reported. The degree of hearing loss was nonrandomly distributed among the three genotype classes (P < 0.0001, Cochran-Mantel-Haenszel test).