Fig 1

Schematic of custom array design. The general design of the custom array is shown where the vertical lines represent the oligonucleotides: one probe is placed every ∼75 kb for the backbone coverage. Other clinically relevant regions, including telomeres, centromeres, common microdeletion/microduplication syndromes and selected Mendelian disorders, contain enhanced coverage. The black bars represent the unique telomere FISH clones and the unique centromere FISH clones that were also targeted on the array.