Fig. 4

Type of significant clinical events first experienced by Fabry Registry patients. Panel A, Data are expressed as the percentage of all deceased or living Fabry Registry males who experienced the indicated events as their first clinical event. Panel B, Data are expressed as the percentage of all deceased or living Fabry Registry females who experienced the indicated events as their first clinical event. Data for deceased patients are shown in black bars, and data for living patients are shown in gray bars, with the number of patients in each age category shown above each bar. The percentages of all patients with renal events and all patients with cardiac events are shown along with the percentages of patients with specific types of renal and cardiac events (indicated in brackets). Note that six deceased males and two deceased females are included in multiple categories, because they experienced more than one type of first event on the same date. Cereb, cerebrovascular.