Fig. 1
From: Guidelines for the prenatal diagnosis of fetal skeletal dysplasias
Three dimensional ultrasound images of fetuses demonstrating the abnormal facial images in thanatophoric dysplasia, achondrogenesis II and achondroplasia. A, Fetus with thanatophoric dysplasia showing severe nasal flattening and distorted facial shape because of craniosynostosis. B, Profile of fetus with thanatophoric dysplasia demonstrating severe nasal flattening and trident configuration of the hands (brachydactyly). C, Fetus with achondrogenesis II showing flattened nasal bridge but no distortion of facial shape. D, Fetus with achondroplasia showing mild flattening of the nasal bridge but not as severe as thanatophoric dysplasia.
