Figure 1

Associations between cancer sites as measured by significantly increased relative risks (RRs) for first-, second-, and third-degree relatives. Associations with P < 0.05 for each of first-, second-, and third-degree relationships are shown. Associations with significantly elevated RRs (P < 0.005) for all three degrees of relationship are shown in bold connecting lines. Single connecting lines show significant excess risk between cancer sites in the direction of the arrow. Sites with two connecting lines between them are significant in both directions. Loops indicate significance for the same site among relatives of probands.