Figure 5

Whole-mount in situ hybridization of myt1la and myt1lb in zebrafish embryos (1–4 days postfertilization (dpf)). The spatial expression of myt1la and myt1lb in zebrafish increases over time and is restricted to the brain. Pictures of embryos during the first 4 days are shown in the lateral view (left) and the dorsal view (right). (a) Expression of myt1la starts in the telencephalon (tel; the forebrain (fb)) during the first 24 hours and extends to more posterior regions (midbrain (mb) and hindbrain (hb)). (b) myt1lb Is initially expressed in the whole central nervous system but stays limited to the different brain regions from 2 dpf on. ey, eye.