Figure 2 | Genetics in Medicine

Figure 2

From: Assessing copy number from exome sequencing and exome array CGH based on CNV spectrum in a large clinical cohort

Figure 2

The relative frequency distribution of the coefficient of variation of the normalized relative coverage for all 180,000 exon targets across a 500-sample baseline. Sixteen percent of exons have coefficients of variation of 0.25 or greater, indicating that a −0.5 change in deviance will not be scored as highly significant; 3.1% of exons have coefficients of variation of 0.5 or greater, indicating extreme relative coverage variability at that target.

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