Figure 1 | Genetics in Medicine

Figure 1

From: Toward an improved definition of the genetic and tumor spectrum associated with SDH germ-line mutations

Figure 1

Spectrum and distribution of SDH germ-line mutations as reported in SDH -deficient tumors including pheochromocytomas (PCCs)/paragangliomas (PGLs), gastrointestinal stromal tumors (GISTs), renal-cell carcinomas (RCCs), and pituitary adenomas (PAs). (a) Percentages of mutations in each SDH gene and of the different types of mutations: frameshift deletion/duplication/insertion (FS), large deletion (LD), missense (MS), nonsense (NS), and splice site (SS). (b) Percentages of the different mutation types for each SDH gene.

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