Figure 1 | Genetics in Medicine

Figure 1

From: Preliminary validation of a consumer-oriented colorectal cancer risk assessment tool compatible with the US Surgeon General’s My Family Health Portrait

Figure 1

Diagram showing the process used for developing interpretations of 150 unmodified pedigrees derived from the ClinSeq population (see text) and resulting calculated values for sensitivity, specificity, PPV, NPV, and calculated κ for the My Family Health Portrait colorectal risk algorithm for detection of elevated colorectal cancer risk using expert genetic counselor pedigree interpretation as the “gold standard” for risk interpretation. CI, confidence interval; NPV, negative predictive value; PPV, positive predictive value; TN, true negative; TP, true positive.

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