Table 1 Germ-line variants in the exonuclease domain (amino acids R311 to L526) and adjacent regions of POLD1 identified in 456 familial or early-onset nonpolyposis CRC and 88 polyposis cases

From: POLE and POLD1 mutations in 529 kindred with familial colorectal cancer and/or polyposis: review of reported cases and recommendations for genetic testing and surveillance