Table 4 Common phenotypic features observed in carriers of pathogenic mutations in the exonuclease domains of POLE and POLD1 reported to date^1–4 and in the current study, and clinical suspicion or recommended guidelines for genetic testing

From: POLE and POLD1 mutations in 529 kindred with familial colorectal cancer and/or polyposis: review of reported cases and recommendations for genetic testing and surveillance