Figure 2
The 10-year absolute risk of being diagnosed with colorectal cancer in men (England, 2001–2012) in the 10th, 50th, and 90th percentiles of a risk model that incorporates common genetic variation (known risk single-nucleotide polymorphisms) and inflammatory bowel disease and where the lower and upper bounds are defined by modifiable lifestyle risk factors. Lower and upper bounds for modifiable risk factors are: alcohol, <5 and ≥50 drinks per week; body mass index, <33 kg/m2 and ≥41 kg/m2; red meat consumption, <5 and ≥5 servings per week; fruit consumption, ≥3 and <3 servings per day; vegetable consumption, ≥5 and <5 servings per day; physical activity, ≥4 and <2 standard deviations above the mean number of hours per day; smoking, never and ever; and aspirin, long-term use and no long-term use.
