Figure 3 | Genetics in Medicine

Figure 3

From: Molecular diagnosis of PIK3CA-related overgrowth spectrum (PROS) in 162 patients and recommendations for genetic testing

Figure 3

Distribution and oncogenic activity of PIK3CA mutations. (a) Distribution of the mutations identified in cases without (dark gray) and with MEG/HMEG (light gray). (b) Oncogenic activity of the identified PIK3CA mutations in cases without (left pane) and with MEG/HMEG (right pane). Oncogenic activity, from weak to strong effect, is illustrated by a gray scale. Mutations with unknown effects are shown in light gray.

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