Figure 1

Kaplan-Meier analyses for a hearing level of 25 decibels (dBHL) in children with the GJB2 p.V37I/p.V37I and the GJB2 p.V37I/c.235delC genotypes. Setting 25 dBHL as the event, 72.4% of children with GJB2 p.V37I/p.V37I and 80.0% of children with GJB2 p.V37I/c.235delC were estimated to have hearing levels <25 dBHL at 3 months. Among children with GJB2 p.V37I/p.V37I and those with GJB2 p.V37I/c.235delC, the percentages with hearing levels <25 dBHL decreased to 48.7 and 48.6%, respectively, at 3 years, and decreased further to 41.0 and 45.7%, respectively, at 5 years. There was no significant difference in the progression of hearing loss between the two groups (Cox hazard ratio, 0.89 (95% confidence interval, 0.54–1.46); P = 0.64).