Figure 2

Kaplan-Meier analyses for a hearing level of 40 decibels (dBHL) in children with the GJB2 p.V37I/p.V37I and the GJB2 p.V37I/c.235delC genotypes. Setting 40 dBHL as the event, 80.4% of children with GJB2 p.V37I/p.V37I and 85.7% of children with GJB2 p.V37I/c.235delC were estimated to have hearing levels <40 dBHL at 3 months. Among children with GJB2 p.V37I/p.V37I and those with GJB2 p.V37I/c.235delC, the percentages with hearing levels <40 dBHL decreased to 76.6 and 80.0%, respectively, at 3 years, and decreased further to 74.7 and 80.0%, respectively, at 5 years. There was no significant difference in the progression of sensorineural hearing impairment between the two groups (Cox hazard ratio, 0.79 (95% confidence interval, 0.35–1.76); P = 0.56).