Figure 3

Linear regressions of hearing levels in children with the GJB2 p.V37I/p.V37I and the GJB2 p.V37I/c.235delC genotypes. Both children with GJB2 p.V37I/p.V37I and those with p.V37I/c.235delC showed progressive sensorineural hearing impairment with time, and the rate of progression did not differ significantly between the two groups. When pooled together, the hearing level in children with GJB2 p.V37I/p.V37I or p.V37I/c.235delC was estimated to deteriorate at approximately 1 decibel hearing level (dBHL)/year (hearing level (dBHL) = 18.7 + 1.0 × year).