Table 1 Descriptive data in the Turner syndrome and control groups
Parameters | All subjects (N = 128) | Turner syndrome (N = 62 (48.4%)) | Controls (N = 66 (51.6%)) | P value |
---|---|---|---|---|
Physical examination and demographic data | ||||
Age (years) | 46.90 ± 12.34 | 47.33 ± 9.23 | 46.50 ± 14.73 | 0.873 |
Body mass index (kg/m2) | 27.82 ± 7.34 | 28.67 ± 8.69 | 27.01 ± 5.75 | 0.734 |
Systolic blood pressure (mm Hg) | 121.80 ± 15.93 | 120.77 ± 17.68 | 122.76 ± 14.16 | 0.238 |
Triglycerides (mg/dl) | 112.97 ± 66.76 | 116.23 ± 73.69 | 109.91 ± 59.94 | 0.610 |
LDL cholesterol (mg/dl) | 103.44 ± 32.00 | 95.56 ± 31.24 | 110.83 ± 31.15 | 0.522 |
HDL cholesterol (mg/dl) | 59.63 ± 17.46 | 60.92 ± 20.36 | 58.41 ± 14.26 | 0.865 |
Total cholesterol (mg/dl) | 186.96 ± 34.74 | 183.61 ± 34.87 | 190.11 ± 34.60 | 0.905 |
Framingham risk score | 1.36 ± 1.79 | 1.05 ± 1.35 | 1.65 ± 2.10 | 0.952 |
Race, N (%) | ||||
Caucasian | 88 (68.8%) | 52 (83.9%) | 36 (54.5%) | 0.002 |
African-American | 26 (20.3%) | 6 (9.7%) | 20 (30.3%) | |
Other | 14 (10.9%) | 4 (6.5%) | 10 (15.2%) | |
Medical history, N (%) | ||||
Hypertension | 52 (40.6%) | 30 (48.4%) | 22 (33.3%) | 0.106 |
History of smoking | 23 (18.0%) | 6 (9.7%) | 17 (25.8%) | 0.022 |
Dyslipidemiaa | 56 (43.8%) | 24 (38.7%) | 32 (48.5%) | 0.289 |
Bicuspid aortic valve | 15 (11.7%) | 15 (24.2%) | 0 (0.0%) | <0.001 |
Coarctation of aorta | 7 (5.5%) | 7 (11.3%) | 0 (0.0%) | <0.001 |
Coronary imaging measurements b | ||||
Calcified plaque, N (%) | 42 (32.8%) | 24 (38.7%) | 18 (27.3%) | 0.191 |
Calcium score (Agatston units)c | 0 (0–11.75) | 0 (0–32.75) | 0 (0–0.875) | 0.502 |
SIS* | 4.5 (2.2–7) | 4 (1.8–7) | 5 (3–8) | 0.960 |
SIS >5, N (%) | 44 (34.4%) | 19 (30.6%) | 25 (37.9%) | 0.458 |
SSS* | 7 (2–12) | 7.5 (2–14) | 6 (2–12) | 0.539 |
SSS >5, N (%) | 71 (55.5%) | 37 (59.7%) | 34 (51.5%) | 0.378 |
SVS* | 5 (3–8) | 5 (1.8–7.2) | 5 (3–9) | 0.912 |