Figure 1
From: Somatic TP53 variants frequently confound germ-line testing results
Consort diagram of the clinical study. The total sample of cases evaluated at the genetic testing laboratory is indicated, followed by the subsets of MGPT and single-gene TP53 tests and the subsets meeting eligibility criteria. Cases that have and have not undergone ancillary testing are noted, as is the final assignment of ACE status, based on consideration of the data. ACE, aberrant clonal expansion; MGPT, multigene panel test; NGS, next-generation sequencing; P, pathogenic; VLP, variant likely pathogenic.
