Table 1 Study population characteristics

From: CGG repeat length and AGG interruptions as indicators of fragile X–associated diminished ovarian reserve

 

Control group ( n  = 86)

All PM patients ( n  = 96)

Midrange group ( n  = 24)

<70 & >90 group ( n  = 72)

P 1

P 2

P 3

CGG repeat length

<55 CGG repeats

55–150 CGG repeats

70–90 CGG repeats

<70 & >90 CGG repeats

Mean age (years) ±SD (range)

34.3 ± 4.6 (24–44)

34 ± 4.6 (24–44)

33.4 ± 4.9 (25–43)

34.3 ± 4.5 (24–44)

0.9

0.8

0.9

Body mass index (kg/m2) ±SD (range)

23.5 ± 5.2 (17–37)

23.3 ± 5.1 (16.5–38)

22.6 ± 4.8 (17–36)

22.8 ± 4.2 (16.5–38)

0.8

0.5

0.8

Mean AMH (ng/ml) ±SD (range)

3.75 ± 3.02 (0.9–18.3)

2.05 ± 3.2 (0.1–15.8)

0.4 ± 0.4 (0.01–1.6)

2.6 ± 3.5 (0.1–15.8)

<0.001

<0.001

0.01

Mean AFC ±SD (range)

16 ± 5 (5–30)

10.3 ± 6.9 (2–25)

5.3 ± 3.4 (2–17)

11.9 ± 7.1 (5–25)

<0.001

<0.001

0.003

Mean retrieved oocytes ±SD (range)

20.9 ± 7.9 (5–36)

8.9 ± 6.2 1.0–26)

4.9 ± 3.6 (1.0–14)

10.2 ± 5.6 (2.0–26)

<0.001

<0.001

<0.001

  1. Summarized are the repeat length, age, body mass index, mean AMH levels, AFC, and retrieved oocytes of the study population (p 1, midrange vs. <70 & >90 group; p 2, control group vs. midrange group; p3-control group vs. <70 & >90 group).
  2. AFC, antral follicle count; AMH, anti-Müllerian hormone; PM, premutation.