Table 2 Study characteristics

From: Are whole-exome and whole-genome sequencing approaches cost-effective? A systematic review of the literature

Statistic

Category

Number of studies (%)

Type of study

Full economic evaluation

8 (22)a

 

Partial economic evaluation

13 (36)

 

Cost study

7 (19)

 

Outcome study

8 (22)

Study setting

Australia

5 (14)

 

Canada

6 (17)

 

France

1 (3)

 

Germany

1 (3)

 

Netherlands

5 (14)

 

Spain

1 (3)

 

UK

4 (11)

 

USA

13 (36)

Sequencing approach

WES (humans)

24 (67)

 

WGS (humans)

5 (14)

 

Both WES and WGS (humans)

5 (14)

 

Bacterial WGS (pathogens)

2 (6)

Study sample size

Not reported

8 (22)

 

<10

4 (11)

 

10–19

5 (14)

 

20–99

10 (28)

 

≥100

9 (25)

Study population

Children or newborns

13 (36)

 

Adults

9 (25)

 

Both adults and children

6 (17)

 

Population unclear

2 (6)

 

No study population

6 (17)

  1. WES, whole-exome sequencing; WGS, whole-genome sequencing.
  2. aTwo cost-utility analyses, six cost-effectiveness analyses.