Figure 1: Pedigrees of the 12 affected families showing 23 affected live-born offspring, 21 of whom underwent molecular analysis with mutational data on the affected children and carrier parents.
From: Autosomal recessive Noonan syndrome associated with biallelic LZTR1 variants
Clinically unaffected children shown not to have two pathogenic variants are indicated with an asterisk (carrier status of minors thereby not disclosed).
