Table 3 Conditional logistic regression analysis results for each attribute and level predicting parental interest in learning child’s sequencing information: main-effects model (N = 1,289)

From: Parental preferences toward genomic sequencing for non-medically actionable conditions in children: a discrete-choice experiment

Attribute

Level

Coeff.

SE

95% CI

P

Relative importance (%)

Likelihood

90%

0.52

0.03

0.47 to 0.57

<0.001

38.5

 

75%

0.21

0.02

0.16 to 0.26

<0.001

 
 

50%

−0.08

0.02

−0.13 to −0.03

0.001

 
 

10%

−0.65

0.03

−0.71 to −0.60

<0.001

 

Age of onset

Less than 1 year

0.15

0.03

0.10 to 0.21

<0.001

12.9

 

1–5 years

0.14

0.03

0.09 to 0.19

<0.001

 
 

6–12 years

−0.06

0.02

−0.11 to −0.01

0.018

 
 

13–18 years

−0.24

0.03

−0.29 to −0.19

<0.001

 

Rate of progression

Rapid

0.18

0.02

0.13 to 0.22

<0.001

9.8

 

Moderate

0.04

0.03

−0.01 to 0.09

0.081

 
 

Slow

−0.12

0.03

−0.17 to −0.07

<0.001

 
 

Stable

−0.10

0.03

−0.15 to −0.05

<0.001

 

Quality of life

Limited options

0.02

0.01

−0.01 to 0.04

0.284

1.0

 

Effective options

−0.02

0.01

−0.04 to 0.01

0.284

 

Level of mental disability

Severe

0.20

0.02

0.16 to 0.25

<0.001

11.8

 

Mild to moderate

−0.03

0.02

−0.07 to 0.01

0.100

 
 

None

−0.17

0.02

−0.21 to −0.13

<0.001

 

Level of physical disability

Severe

0.19

0.02

0.15 to 0.23

<0.001

12.4

 

Mild to moderate

−0.01

0.02

−0.05 to 0.03

0.529

 
 

None

−0.17

0.02

−0.21 to −0.13

<0.001

 

Life span

Shortened

0.21

0.01

0.18 to 0.24

<0.001

13.6

 

Normal

−0.21

0.01

−0.24 to −0.18

<0.001

 
  1. Number of observations = 20,624; χ2(15) = 1,407.80; P<0.001; Pseudo R2 = 0.10.