Figure 2 | Gene Therapy

Figure 2

From: Cells as vehicles for therapeutic genes to treat liver diseases

Figure 2

Recruitment of endothelial progenitor cell (EPC) transduced by adenoviral vector encoding firefly luciferase reporter gene in orthotopic liver cancer. C57BL/6 mice received MC38 colon carcinoma cells to induce a liver tumor. After 10 days, 106 of EPC transduced with adenovirus expressing luciferase were intravenously injected into tumor-bearing animals. Luciferase-positive EPC are recruited by the tumor being detected by immunohistochemistry using antibody against luciferase. Arrows indicate luciferase positive cells.

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