Figure 1 | Gene Therapy

Figure 1

From: Noncarrier naked antigen-specific DNA vaccine generates potent antigen-specific immunologic responses and antitumor effects

Figure 1

Fluorescence studies on skins of gold particle-coated or noncarrier naked pcDNA3-green fluorescence protein (GFP) DNA vaccinated mice. (a) Gold particle-coated DNA 6 h after immunization. (b) Noncarrier naked DNA in distilled H2O (ddH2O) solution 6 h after immunization. (c) Noncarrier naked DNA in phosphate-buffered saline (PBS) 6 h after immunization. (d) Noncarrier naked DNA in Tris-EDTA (TE) solution 6 h after immunization (note: only a few cells in the intradermis expressed the GFP protein). (e) Gold particle-coated DNA 1 day after immunization. (f) Noncarrier naked DNA in ddH2O solution 1 day after immunization. (g) Noncarrier naked DNA in PBS solution 1 day after immunization. (h) Noncarrier naked DNA in TE solution 1 day after immunization (note: most of the cells in the intradermis expressed the GFP protein).

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