Figure 6 | Gene Therapy

Figure 6

From: Development of the hybrid Sleeping Beauty-baculovirus vector for sustained gene expression and cancer therapy

Figure 6

Bac-SB-T2hEA/w conferred antitumor effects in human ovarian tumor xenografts. (a) Tumor volume. (b) Percent survival. Human SKOV3 cells (1 × 106 cells per mouse) were injected subcutaneously into the back of BALB/c nu/nu mice (n=4 for each group). When the tumor volume reached 70 mm3, PBS, Bac-SB-T2luc/w or Bac-SB-T2hEA/w was injected intratumorally at days 0, 3 and 6. **Indicates the significant difference (P<0.005) between the Bac-SB-T2luc/w and Bac-SB-T2hEA/w groups.

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