Figure 2 | Gene Therapy

Figure 2

From: Plasmid-based transient human stromal cell-derived factor-1 gene transfer improves cardiac function in chronic heart failure

Figure 2

(a) Dose–response of cardiac gene expression. Rodent hearts were injected with varying doses of pCMV-Luc into the anterior wall. The chemiluminescence emitted was measured everyday for 5 days after the injection. (b) Comparison of cardiac bioluminescence between vectors. Animals were injected with pCMV Luc (n=5), pCMVe Luc (n=3) and pMHC Luc (n=7) and expression monitored by quantifying the chemiluminescence emitted. (c) Duration of vector expression. The peak chemiluminescence exhibited by the vectors is shown here. pCMV-Luc (n=5), pCMVe-Luc (n=3) and pMHC-Luc (n=7). *P<0.05.

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