Figure 2
From: Erratum: Long-term VEGF-A expression promotes aberrant angiogenesis and fibrosis in skeletal muscle
Muscle perfusion imaged by contrast pulse sequence (CPS) ultrasound technique in normal muscles (a–d) and after ischemia operation (e–h). Native image after AAV-VEGF-A-A165 injection, asterisk indicates the location of the injection (a). CPS images from the same muscle 1 month (b) and 12 months (d) after AAV-VEGF-A-A165 gene transfer. Power Doppler image after AAV-VEGF-A-A165 gene transfer (c). Power Doppler (e) and CPS (f) images 6 months after ischemia operation and AAV-LacZ gene transfer. Power Doppler (g) and CPS (h) images 6 months after ischemia operation and AAV-VEGF-A-A165 gene transfer. Arrowheads in Doppler images indicate the signal from large vessels. Perfusion ratio to contralateral intact in normal muscles (i) and in ischemic muscles (j). Perfusion in VEGF-A-transduced muscle was increased compared with LacZ muscle already 1 week after gene transfer both in normoxic and in ischemic muscles. Results are presented as means±s.e.m., *P⩽0.05, n=3.
