Figure 1 | Gene Therapy

Figure 1

From: Inhibition of neointimal hyperplasia in a rabbit vein graft model following non-viral transfection with human iNOS cDNA

Figure 1

X-Gal staining of 7-day vein graft samples. (a) Gross sample of vein graft transfected with β-Gal. The portion between the outer black sutures (arrowed) is the vein graft. The inner arrow points to the suture for the branch off the jugular vein. Positive (blue) X-Gal staining was contrasted with the pale colour of adjacent untransfected arterial portions at both ends. (b) X-Gal staining of β-Gal-transfected 7-day vein graft section. Blue, X-Gal-positive cells were abundant across the adventitia with some in the intima. (c) View of higher magnification of the highlighted area in (b). (d) X-Gal staining on control plasmid pCI-transfected vein graft. Images are representatives of three samples in each group. A, adventitia and peri-adventitia; I, intimal layer; Lu, lumen; M, medial layer. Bars=100 μm.

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