Figure 1 | Gene Therapy

Figure 1

From: Effect of vascular endothelial growth factor gene therapy on post-traumatic peripheral nerve regeneration and denervation-related muscle atrophy

Figure 1

Histograms showing viral DNA as well as transgene expression in the injected tissues. Peripheral nerve regeneration model (a and b; number of rats analyzed=16): quantification of viral DNA in the pectoralis major muscle used to fill the MIV conduit at the moment of surgery and in the MIV conduits 14 days after surgery, quantified by real-time PCR (a); transgene relative expression quantification in the pectoralis major muscle used to fill the MIV conduit at the moment of surgery and in the MIV conduits 14 days after surgery; results are expressed after normalization over the levels of the housekeeping gene GAPDH (b). Skeletal muscle atrophy model (c and d; number of rats analyzed=8): quantification of viral DNA in the flexor digitorum sublimis muscle withdrawn 14 days after denervation and infection, quantified by real-time PCR (c); transgene relative expression quantification in the flexor digitorum sublimis muscle withdrawn 14 days after denervation and infection; results are expressed after normalization over the levels of the housekeeping gene GAPDH (d).

Back to article page