Figure 6 | Gene Therapy

Figure 6

From: CD40 ligand and tdTomato-armed vaccinia virus for induction of antitumor immune response and tumor imaging

Figure 6

Efficacy of vvdd-hCD40L-tdTomato in CD40-negative tumors following intravenous administration. Nude mice bearing human tumors were treated with PBS, vvdd-tdTomato and vvdd-hCD40L-tdTomato, and tumor growth was measured over time. Administration of the virus was performed intravenously. (a) hCD40L-sensitive breast tumors (EJ cell line). (b) hCD40 negative tumors (A549 cell line).

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