Table 1 Proportion of spinal transduced MNs in cats injected with scAAV9-CMV-GFP by intracisternal route

From: Intracisternal delivery of AAV9 results in oligodendrocyte and motor neuron transduction in the whole central nervous system of cats

Age at injection

Cat

Proportion of GFP-positive MNs

  

Cervical enlargement

Lumbar enlargement

2 days (newborn)

C1

51.4±3.3

100

 

C2

100

100

 

C3

98.7±1.3

99.7±0.3

50 days (young)

C4

100

100

 

C5

48.2±3.2

95.6±2.3

 

C6

100

100

  1. Abbreviations: C, cat; CMV, cytomegalovirus; GFP, green fluorescent protein; MN, motor neuron; scAAV, self-complementary adeno-associated virus.
  2. Results are expressed as means± s.e.m.
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