Figure 3 | Gene Therapy

Figure 3

From: Mucopolysaccharidosis IIIB confers enhanced neonatal intracranial transduction by AAV8 but not by 5, 9 or rh10

Figure 3

rAAVs exhibit differences in GFP production in MPS IIIB brain as indicated by resulting GFP intensity. Mid-sagittal sections of 3-month-old MPS IIIB animals were used to quantitate intensity of AAV-based GFP production. GFP intensities in the cortex, hippocampus, thalamus and cerebellum of each animal were summed. Data were analyzed by one-way ANOVA. **P<0.01, $P<0.0001. Data represented as mean±s.e.m., N=3/serotype.

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