Figure 5 | Gene Therapy

Figure 5

From: Mucopolysaccharidosis IIIB confers enhanced neonatal intracranial transduction by AAV8 but not by 5, 9 or rh10

Figure 5

Differences in GFP intensity of transduced cells are observed based on AAV serotype. GFP intensity of AAV transduced neurons and astrocytes was assessed in MPS IIIB animals at 3 months of age. Serotype-dependent differences in GFP intensity were determined using APERIO ScanScope FL Positive Pixel Count FL algorithm and quantitated using Student’s t-test. N=3/serotype, **P<0.01, $P<0.0001. Data represented as mean±s.e.m.

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