Table 1 Mutations of surface-exposed tyrosine (Y), serine (S), threonine (T) and Lysine (K) residues in combination with RGD peptide insertion on the AAV6 capsid
From: Development of novel AAV serotype 6 based vectors with selective tropism for human cancer cells
AAV6 with RGD and Mutations |
|---|
S663V |
K531E |
T492V+S663V |
S663V+K531E |
Y705-731F+K531E |
T492V+S663V+K531E |
Y705-731F+T492V (3M) |
Y705-731F+T492V+K531E |
RGD |
RGD+S663V |
RGD+K531E |
RGD+S663V+K531E |
RGD+T492V+S663V |
RGD+T492V+S663V+K531E |
RGD+Y705-731F+T492V |
RGD+Y705-731F+T492V+K531E |
