Figure 8
From: Ultrasound-targeted hepatic delivery of factor IX in hemophiliac mice
ALT assay on treated mutant mouse plasma. Average ALT levels 1, 4 or 5 and 12 days after UTMD treatment with pZY53-hFIX (n=4 for day 1 and n=3 for days 4 or 5 and 12 time points) or pmGENIE3-hFIX (n=4 per time point). Untreated wild-type, mutant and pZY53-luc-treated mouse plasma served as controls (n=1 per control group).
