Table 1 Usher syndrome genes that are large or alternatively spliced

From: Gene therapy approaches for prevention of retinal degeneration in Usher syndrome

USH Subtype

Gene

Number of isoforms

Length (amino acids)

Reference

USH1B

MYO7A

2a

2175, 2215

17

USH1C

USH1C

3 classesa,b

Up to 899

32

USH1D

CDH23

3 classesc,b

Up to 3354

33

USH1F

PCDH15

3 classesa,b

Up to 1955

34

USH1G

SANS

2c

358, 461

 

USH1J

CIB2

3c

Up to 210

35

USH2A

USH2A

2a

Up to 5202

36

USH2C

GPR98

3a

Up to 6306

37

USH2D

WHRN

3c

Up to 907

38

USH3A

CLRN1

11a

Up to 245

39

  1. aExpressed in the human retina.
  2. bEach class represents multiple isoforms.
  3. cTotal number expressed in human; the number in the retina is not known.