Figure 3
From: Optimization of lentiviral vector production for scale-up in fixed-bed bioreactor
Glucose consumption in iCELLis Nano. (a) Glucose and (b) lactate concentrations measured daily from cell culture medium. (c) Glucose and lactate levels in bioreactor (run 6) and respective control flasks, and cell growth (n=3 mean±s.d.) in bioreactor from inoculation to harvest. (d) Glucose consumption per cell per day in run with fixed perfusion rate and in runs when targeting low or high glucose concentration by adjusting perfusion rates. (e) Correlation between cell density and glucose consumption cm–2.
