Summary
The growth of yeast cultures at supra-optimal temperatures up to 39°C and exposure in non-nutrient solution up to 52 °C has been examined for the induction of genetic change. Both sets of conditions lead to the induction of mutation to antibiotic resistance, mitotic gene conversion, crossing-over and mitotic chromosomal non-disjunction.
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Evans, W., Parry, J. The genetic effects of elevated temperature in the yeast, Saccharomyces cerevisiae. Heredity 35, 347–359 (1975). https://doi.org/10.1038/hdy.1975.105
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DOI: https://doi.org/10.1038/hdy.1975.105
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