Summary
Positive cross-over interference is attributed to the prevention of crossing-over by the growing synaptonemal complex. This conjecture is based on a report in the literature that the selection of prospective cross-over sites may actually precede a proper synapsis of homologous chromosomes during meiotic prophase. A genetic test of this notion is suggested using a properly marked trisomic configuration, applicable to a variety of organisms.
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References
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Egel, R. Synaptonemal complex and crossing-over: structural support or interference?. Heredity 41, 233–237 (1978). https://doi.org/10.1038/hdy.1978.92
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DOI: https://doi.org/10.1038/hdy.1978.92
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