Summary
In theory, a matched pair of crosses in which the pure breeding parents display association and dispersion for the same alleles at the same loci provides sensitive tests for the presence of complex sources of variation. Thus comparison of the genetical component of variation within the F2 and first backcross families of such a pair of crosses can detect and distinguish between non-allelic interaction, a linkage disequilibrium of non-interacting genes and a linkage disequilibrium of interacting genes.
These theoretical expectations are confirmed by analyses of two sets of matched association and dispersion pairs of crosses involving pure breeding varieties 1 and 5, and 2 and 12 of Nicotiana rustica and pure breeding selections for final height extracted from crosses between them by single seed descent. Furthermore, these analyses show that comparison of the genetical components of the variation within F2, B1 and B2 families of matched association and dispersion crosses are more sensitive to non-allelic interaction and linkage disequilibrium than much larger and more complex experiments based on a single cross and analysed by conventional model fitting procedures.
Similar content being viewed by others
Article PDF
References
Jayasekara, N E M, and Jinks, J L. 1976. Effect of gene dispersion on estimates of components of generation means and variances. Heredity, 36, 31–40.
Jinks, J L. 1954. The analysis of continuous variation in a diallel cross of Nicotiana rustica varieties. Genetics, 39, 767–788.
Jinks, J L. 1956. The F2 and backcross generations from a set of diallel crosses. Heredity, 10, 1–30.
Jinks, J L. 1978. Unambiguous test for linkage of genes displaying non-allelic interactions for a metrical trait. Heredity, 40, 171–173.
Jinks, J L, Jayasekara, N E M, and Boughey, H. 1977. Joint selection for both extremes of mean performance and of sensitivity to a macro-environmental variable. II. Single seed descent. Heredity, 39, 345–355.
Jinks, J L, and Jones, R M. 1958. Estimation of the components of heterosis. Genetics, 43, 233–234.
Jinks, J L, and Perkins, J M. 1969. The detection of linked epistatic genes for a metrical trait. Heredity, 24, 465–475.
Jinks, J L, and Perkins, J M. 1972. Predicting the range of inbred lines. Heredity, 28, 399–403.
Mather, K. 1949. Biometrical Genetics, First edition. Methuen, London.
Mather, K. 1967. Complementary and duplicate gene interactions in biometrical genetics. Heredity, 22, 97–103.
Mather, K, and Jinks, J L. 1971. Biometrical Genetics, Second edition, Chapman and Hall, London.
Mather, K, and Jinks, J L. 1982. Biometrical Genetics, Third edition, Chapman and Hall, London.
Opsahl, B. 1956. The discrimination of interaction and linkage in continuous variation. Biometrics, 12, 415–432.
Perkins, J M, and Jinks, J L. 1970. Detection and estimation of genotype-environmental, linkage and epistatic components of variation for a metrical trait. Heredity, 25, 157–177.
Pooni, H S, and Jinks, J L. 1981. The true nature of the non-allelic interactions in Nicotiana rustica revealed by association crosses. Heredity, 47, 253–258.
Pooni, H S, Jinks, J L, and Jayasekara, N E M. 1978. An investigation of gene action and genotype × environmental interaction in two crosses of Nicotiana rustica by triple test cross and inbred line analysis. Heredity, 41, 83–92.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Pooni, H., Jinks, J. Comparative analysis of association and dispersion crosses to detect linkage and epistatic components of variation. Heredity 49, 211–220 (1982). https://doi.org/10.1038/hdy.1982.87
Received:
Issue date:
DOI: https://doi.org/10.1038/hdy.1982.87
This article is cited by
-
Predicting and observing the properties of second cycle hybrids using basic generations and inbred line × F1 crosses
Heredity (1985)
-
Comparison of inbred lines produced by single seed descent and pedigree inbreeding
Heredity (1984)
-
Comparison of associated and dispersed testers in the triple test cross
Heredity (1983)
