Summary
Kinetics of the mating-type interconversion was observed after heterothallic nutritionally-marked stocks of Kluyveromyces lactis were mated and sporulated. Conversion to homothallism is not finished within the period of 10 days of growth on the sporulation agar. In general, the expression of homothallism in the α mating-type is often delayed when compared to the a mating-type. Segregation patterns of tetrads suggest the functioning of a mating-type interconversion system including a mating locus and two silent storage copies of the mating-type information.
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Egel, R, and Gutz, H. 1981. Gene activation by copy transposition in mating-type switching of a homothallic fission yeast. Current Genet, 3, 5–12.
Harashima, S, Nogi, Y, and Oshima, Y. 1974. The genetic system controlling homothallism in Saccharomyces yeast. Genetics, 77, 639–650.
Harashima, S, and Oshima, Y. 1976. Mapping of the homothallic genes HMα and HMa in Saccharomyces yeasts. Genetics, 84, 437–451.
Herman, A, and Roman, H L. 1966. Allele specific determinants of homothallism in Saccharomyces lactis. Genetics, 53, 727–740.
Herskowitz, I, Strathern, J N, Hicks, J B, and Rine, J. 1977. Mating-type interconversion in yeast and its relationship to development in higher eucaryotes. In Wilcox, G., Abelson, J., and Fox, C. F. (eds.) Eucaryotic Genetic Systems, ICN - UCLA Symp. on Molec. and Cellul. Biology, Vol. 8, Academic Press, New York, pp. 193–202.
Hicks, J B, Strathern, J N, and Herskowitz, I. 1977. The casette model of mating-type interconversion. In Bukhari, A., Shapiro, J., and Adhya, S. (eds.) DNA Insertion Elements, Plasmids and Episomes, Cold Spring Harbor Laboratory, New York, pp. 457–462.
Klar, A J S, Hicks, J B, and Strathern, J N. 1982. Directionality of yeast mating-type interconversion. Cell, 28, 551–561.
Klar, A J S, Strathern, J N, and Hicks, J B. 1981a. A position-effect control for gene transposition: State of expression of yeast mating-type genes affects their ability to switch. Cell, 25, 517–524.
Klar, A J S, Strathern, J N, Broach, J R, and Hicks, J B. 1981b. Regulation of transcription in expressed and unexpressed mating-type cassettes of yeast. Nature, 289, 239–243.
Mortimer, R K, and Hawthorne, D C. 1969. Yeast genetics. In Rose, A. H., and Harrison, J. S. (eds.) The Yeasts, Part 1, Academic Press, New York, pp. 385–460.
Nasmyth, K A, Tatchell, K, Hall, B D, Astell, C, and Smith, M. 1981. A position effect in the control of transcription at yeast mating-type loci. Nature, 289, 244–249.
Naumov, G I, and Tolstorukov, I I. 1973. Comparative genetics of yeast. X. Reiden-tificatiuon of mutators of mating-types in Saccharomyces. Genetika, 9, 82–91.
Oshima, Y, and Takano, I. 1971. Mating-types in Saccharomyces: Their convertibility and homothallism. Genetics, 67, 327–335.
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Novotnẏ, Č., Fuentes, JL., Carré, P. et al. Homothallism expression in Kluyveromyces lactis. Heredity 51, 549–559 (1983). https://doi.org/10.1038/hdy.1983.70
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DOI: https://doi.org/10.1038/hdy.1983.70