Abstract
Accurate estimates of the true additive genetic variance (
) of a cross between two pure breeding varieties can be obtained from the additive genetic components of the first three ranks (D1, D2 and D3) when the latter are biased by the presence of linkage. Additive genetic variances of the lower ranks are directly equatable with because they incur minimal bias even when the predominating linkages are strong. More precise estimates of are however obtainable from the asymptotic regression analysis or a weighted least squares analysis.
Estimates of when obtained from 784 hierarchically derived F7 families of the V2 × V12 cross of Nicotiana rustica were observed to be considerably larger than the additive genetic variance displayed by the F13 inbreds of the same cross for all the characters that showed significant excess of repulsion linkages. These results lend support to our commonly held view that the prediction procedures generally underestimate the probability of successful recovery of superior recombinant inbreds.
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Pooni, H., Jinks, J. Estimation of the true additive genetic variance in the presence of linkage disequilibrium. Heredity 57, 341–344 (1986). https://doi.org/10.1038/hdy.1986.133
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DOI: https://doi.org/10.1038/hdy.1986.133
